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Hypertension and hypothyroidism

1998; Springer Nature; Volume: 12; Issue: 2 Linguagem: Inglês

10.1038/sj.jhh.1000574

1476-5527

AK Fletcher, AP Weetman,

Thyroid Disorders and Treatments

Correction of the causes of secondary forms of hypertension usually restores blood pressure to normal. Hypothyroidism is a potentially important but overlooked cause of hypertension and restoration of euthyroidism with thyroxine therapy usually results in a substantial reduction in both systolic and diastolic blood pressure, especially in younger subjects. The mechanism of hypertension in hypothyroidism is not completely understood: changes in circulating catecholamines, their receptors and the renin-angiotensin-aldosterone system have all been implicated. Effective treatment with thyroxine is readily available and inexpensive.