Portal de Periódicos da CAPES

High‐rate pulmonary involvement in autoimmune pancreatitis

2005; Wiley; Volume: 36; Issue: 1 Linguagem: Inglês

10.1111/j.1445-5994.2006.01009.x

1445-5994

Kenji Hirano, Takeshi Kawabe, Yutaka Komatsu, Saburo Matsubara, Osamu Togawa, Toshihiko Arizumi, Natsuyo Yamamoto, Yousuke Nakai, Naoki Sasahira, Takuya Tsujino, Nobuo Toda, Hiroyuki Isayama, Minoru Tada, Masao Omata,

Pancreatitis Pathology and Treatment

Abstract Autoimmune pancreatitis (AIP) has extrapancreatic complications such as Sjögren's syndrome, retroperitoneal fibrosis and sclerosing cholangitis. We studied 30 patients with AIP. Of these, we identified pulmonary involvement in four patients during follow up. Among them, two patients had respiratory failure. They showed good response to steroid therapy, but a higher dose of prednisolone was necessary to maintain remission than that required in biliary involvement. Elevation of immunoglobulin G 4 and Krebs von den Lungen‐6 levels were characteristic of pulmonary involvement. They may be useful for early detection of pulmonary complication.