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Application of the gamma evaluation method in Gamma Knife film dosimetry

2011; Wiley; Volume: 38; Issue: 10 Linguagem: Inglês

10.1118/1.3641644

2473-4209

Jeong‐Hoon Park, Jung Ho Han, Chae‐Yong Kim, Chang Wan Oh, Do-Heui Lee, Tae Suk Suh, Dong Gyu Kim, Hyun‐Tai Chung,

Medical Imaging Techniques and Applications

Medical PhysicsVolume 38, Issue 10 p. 5778-5787 Radiation therapy physics Application of the gamma evaluation method in Gamma Knife film dosimetry Jeong-Hoon Park, Jeong-Hoon Park Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam 463-707, Korea and Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea Seoul 137-701, KoreaSearch for more papers by this authorJung Ho Han, Jung Ho Han Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam 463-707, Korea and Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, KoreaSearch for more papers by this authorChae-Yong Kim, Chae-Yong Kim Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam 463-707, Korea and Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, KoreaSearch for more papers by this authorChang Wan Oh, Chang Wan Oh Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam 463-707, Korea and Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, KoreaSearch for more papers by this authorDo-Heui Lee, Do-Heui Lee Department of Neurosurgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul 138-736, KoreaSearch for more papers by this authorTae-Suk Suh, Tae-Suk Suh Department of Biomedical Engineering and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea Author to whom correspondence should be addressed. Electronic mail: [email protected]; [email protected]Search for more papers by this authorDong Gyu Kim, Dong Gyu Kim Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, KoreaSearch for more papers by this authorHyun-Tai Chung, Hyun-Tai Chung Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, Korea Author to whom correspondence should be addressed. Electronic mail: [email protected]; [email protected]Search for more papers by this author Jeong-Hoon Park, Jeong-Hoon Park Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam 463-707, Korea and Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea Seoul 137-701, KoreaSearch for more papers by this authorJung Ho Han, Jung Ho Han Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam 463-707, Korea and Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, KoreaSearch for more papers by this authorChae-Yong Kim, Chae-Yong Kim Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam 463-707, Korea and Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, KoreaSearch for more papers by this authorChang Wan Oh, Chang Wan Oh Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam 463-707, Korea and Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, KoreaSearch for more papers by this authorDo-Heui Lee, Do-Heui Lee Department of Neurosurgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul 138-736, KoreaSearch for more papers by this authorTae-Suk Suh, Tae-Suk Suh Department of Biomedical Engineering and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea Author to whom correspondence should be addressed. Electronic mail: [email protected]; [email protected]Search for more papers by this authorDong Gyu Kim, Dong Gyu Kim Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, KoreaSearch for more papers by this authorHyun-Tai Chung, Hyun-Tai Chung Department of Neurosurgery, College of Medicine, Seoul National University, Seoul 110-799, Korea Author to whom correspondence should be addressed. Electronic mail: [email protected]; [email protected]Search for more papers by this author First published: 27 September 2011 https://doi.org/10.1118/1.3641644Citations: 15 Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Purpose : Gamma Knife (GK) radiosurgery is a minimally invasive surgical technique for the treatment of intracranial lesions. To minimize neurological deficits, submillimeter accuracy is required during treatment delivery. In this paper, the delivery accuracy of GK radiosurgery was assessed with the gamma evaluation method using planning dose distribution and film measurement data. Methods : Single 4, 8, and 16 mm and composite shot plans were developed for evaluation using the GK Perfexion (PFX) treatment planning system (TPS). The planning dose distributions were exported as digital image communications in medicine – radiation therapy (DICOM RT) files using a new function of GK TPS. A maximum dose of 8 Gy was prescribed for four test plans. Irradiation was performed onto a spherical solid water phantom using Gafchromic EBT2 films in the axial and coronal planes. The exposed films were converted to absolute dose based on a 4th-order polynomial calibration curve determined using ten calibration films. The film measurement results and planning dose distributions were registered for further analysis in the same Leksell coordinate using in-house software. The gamma evaluation method was applied to two dose distributions with varying spatial tolerance (0.3–2.0 mm) and dosimetric tolerance (0.3–2.0%), to verify the accuracy of GK radiosurgery. The result of gamma evaluation was assessed using pass rate, dose gamma index histogram (DGH), and dose pass rate histogram (DPH). Results : The 20, 50, and 80% isodose lines found in film measurements were in close agreement with the planning isodose lines, for all dose levels. The comparison of diagonal line profiles across the axial plane yielded similar results. The gamma evaluation method resulted in high pass rates of >95% within the 50% isodose line for 0.5 mm/0.5% tolerance criteria, in both the axial and coronal planes. They satisfied 1.0 mm/1.0% criteria within the 20% isodose line. Our DGH and DPH also showed that low isodose lines exhibited inferior gamma indexes and pass rates compared with higher isodose lines. 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