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Recognition of Cancer in vivo by Nuclear Magnetic Resonance

1972; American Association for the Advancement of Science; Volume: 178; Issue: 4067 Linguagem: Inglês

10.1126/science.178.4067.1288

1095-9203

I. D. Weisman, Lawrence H. Bennett, Louis R. Maxwell, Mark Woods, Dean Burk,

Electron Spin Resonance Studies

Pulsed nuclear magnetic resonance has been used to differentiate in vivo between normal mouse tail tissue and a malignant transplanted melanoma, S91, located on the tail. The tumor displayed a nuclear (proton) spin-lattice relaxation time of approximately 0.7 second contrasted with the simultaneously measured normal tail tissue relaxation time of approximately 0.3 second.