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Artigo Revisado por pares
BIBTEX RIS

CD4 + T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer

2013; American Association for the Advancement of Science; Volume: 5; Issue: 215 Linguagem: Inglês

10.1126/scitranslmed.3007320

ISSN

1946-6242

Autores

Laura Passerini, Eva Rossi Mel, Claudia Sartirana, Georgia Fousteri, Attilio Bondanza, Luigi Naldini, Maria Grazia Roncarolo, Rosa Bacchetta,

Tópico(s)

CAR-T cell therapy research

Resumo

FOXP3 gene transfer in FOXP3 -mutated CD4 + T cells is feasible and converts IPEX conventional T cells into regulatory T cells.

Referência(s)