Alkaloids from leaves and root bark ofErvatamia hirta
1991; Elsevier BV; Volume: 30; Issue: 11 Linguagem: Inglês
10.1016/0031-9422(91)80111-d
ISSN1873-3700
AutoresPascale Clivio, Bernard Richard, Jean-Robert Deverre, Thierry Sévenet, Monique Zèches, Louisette Le Men-Oliver,
Tópico(s)Plant chemical constituents analysis
ResumoDuring chemical investigation of the leaves and root bark ofErvatamia hirta, 33 alkaloids were isolated. Seven are new: six are the 'monomeric' alkaloids (E) 16-epi-normacusineB, (E) 16-epi-affinisine,O-acetyl-16-epi-affinisine, affinisine-N(4)-oxide, dehydro-16-epi-affinisine, norfluorocurarine-N(4)-oxide, and the seventh is the bisindole 16-decarbomethoxyvoacamine-pseudoindoxyl. The known alkaloids are: (E) 16-epi-isositsirikine, β-yohimbine, yohimbine, 19,20-dehydro-β-yohimbine, β-yohimbine-pseudoindoxyl, isositsirikine, 19,20-dihydroisositsirikine, β-yohimbine-oxindole, normacusineB, affinisine, vobasine, dregamine, tabernaemontanine, norfluorocurarine, 12-hydroxynorfluorocurarine, apparicine, 3,14-dihydroellipticine, antirhine, voacristine, ibogaine, i☐ygaine, i☐ygaine-hydroxyindolenine, iboluteine, 4′,17,(17β)-dihydrotchibangensine, 16-decarbomethoxyvoacamine and 19,20-dihydro-16-decarbomethoxyvoacamine. Structural elucidation of the new alkaloids is based on spectral data and chemical correlations.
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