Synthesis of heterocyclic ketene N,O‐Acetals and their reactions with α,β‐unsaturated esters

1989; Wiley; Volume: 122; Issue: 10 Linguagem: Inglês

10.1002/cber.19891221029

ISSN

0009-2940

Autores

Zhi‐Tang Huang, Pingcheng Zhang,

Tópico(s)

Synthesis and Characterization of Heterocyclic Compounds

Resumo

Abstract Ketene dithioacetals 2 react with 2‐aminoethanol or 1‐amino‐2‐propanol to afford the corresponding substituted 2‐methyleneoxazolidines 3 and 4 . In some cases, 3 and 4 react with α,β‐unsaturated esters to give 5 H ‐oxazolo[3,2‐ a ]pyridine derivatives 5 by an electrophilic addition and cyclocondensation sequence.

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