Portal de Periódicos da CAPES

Comparison of hydrolases, peroxidase and protease inhibitors in bronchalveolar fluid from Macacus cynomolgus and human controls

1987; Elsevier BV; Volume: 88; Issue: 2 Linguagem: Inglês

10.1016/0305-0491(87)90359-2

0305-0491

Marie-Hélène Hannothiaux, Andrée Scharfman, Jean‐Jacques Lafitte, Line Cornut, Henriette Daniel, Philippe Roussel,

Neonatal Respiratory Health Research

1. Serial bronchoalveolar lavages were performed on a subhuman primate (Macacus cynomolgus) in order to give an experimental model for silicosis. 2. We have measured glycosidases, proteases, peroxidase and antiproteases of the BAL fluids from seven normal monkeys. 3. The results obtained were similar to those found in human control BAL fluids. 4. For monkeys, the repetition of the bronchoalveolar procedure does not seem to have an important influence on the values obtained. 5. The present results will now permit sequential follow up studies during the course of experimental silicosis.