Portal de Periódicos da CAPES

Combinatorial biosynthesis of polyketides and nonribosomal peptides

2001; Elsevier BV; Volume: 5; Issue: 2 Linguagem: Inglês

10.1016/s1367-5931(00)00185-x

1879-0402

James Staunton, Barrie Wilkinson,

Phytochemical compounds biological activities

The engineering of polyketide biosynthesis has begun to provide robust targeted libraries for screening against pharmaceutically relevant targets. New technologies that offer methodology for the rapid generation of more structurally diverse libraries have now been demonstrated.