1,5-annelated 4-methylenecyclopentenes by intramolecular type I zinc-ene reactions followed by Pd(0)-catalyzed cyclization
1989; Elsevier BV; Volume: 30; Issue: 33 Linguagem: Inglês
10.1016/s0040-4039(00)99387-0
ISSN1873-3581
AutoresJ. Van Der Louw, C.M.D. Komen, Adri Knol, F.J.J. De Kanter, J. L. VAN DER BAAN, F. Matthias Bickelhaupt, G. W. Klumpp,
Tópico(s)Catalytic C–H Functionalization Methods
Resumo3-(Alk-m-ynyl)-2-(methoxymethyl)-2-propenylzinc bromides 1 (m = 4,5,6) undergo intramolecular carbometallation. The products 2 were converted by Pd(0)-catalyzed cyclization to 1,5-annelated 4-methylenecyclopentenes 3.
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