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State of the art and future directions in nanomedicine for tuberculosis

2013; Taylor & Francis; Volume: 10; Issue: 12 Linguagem: Inglês

10.1517/17425247.2014.846905

1744-7593

Admire Dube, Yolandy Lemmer, Rose Hayeshi, Mohammed O. Balogun, Philip Labuschagne, Hulda Swai, Lonji Kalombo,

Orthopedic Infections and Treatments

Introduction: Tuberculosis (TB) ranks the second leading cause of death from an infectious disease worldwide. However, treatment of TB is affected by poor patient compliance due to the requirement for daily drug administration, for lengthy periods of time, often with severe drug-induced side effects. Nanomedicines have the potential to improve treatment outcomes by providing therapies with reduced drug doses, administered less frequently, under shortened treatment durations.