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Polymorphism in Detoxifying Enzymes and Susceptibility to Skin Cancer

1996; Wiley; Volume: 63; Issue: 4 Linguagem: Inglês

10.1111/j.1751-1097.1996.tb03062.x

1751-1097

John T. Lear, Adrian Heagerty, Andrew G. Smith, Bill Bowers, Peter W. Jones, Janice Gilford, Julie Alldersea, Anthony A. Fryer, Richard C. Strange,

Skin Protection and Aging

Photochemistry and PhotobiologyVolume 63, Issue 4 p. 424-428 Free Access Polymorphism in Detoxifying Enzymes and Susceptibility to Skin Cancer J. Lear, J. Lear departments of Dermatology, North Staffordshire Hospital and Royal Cornwall HospitalsSearch for more papers by this authorA. Heagerty, A. Heagerty departments of Dermatology, North Staffordshire Hospital and Royal Cornwall HospitalsSearch for more papers by this authorA. Smith, A. Smith departments of Dermatology, North Staffordshire Hospital and Royal Cornwall HospitalsSearch for more papers by this authorB. Bowers, B. Bowers departments of Dermatology, North Staffordshire Hospital and Royal Cornwall HospitalsSearch for more papers by this authorP. Jones, P. Jones department of Mathematics, Keele UniversitySearch for more papers by this authorJ. Gilford, J. Gilford Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, North Staffordshire Hospital, UKSearch for more papers by this authorJ. Alldersea, J. Alldersea Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, North Staffordshire Hospital, UKSearch for more papers by this authorA. Fryer, A. Fryer Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, North Staffordshire Hospital, UKSearch for more papers by this authorR. Strange, R. Strange Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, North Staffordshire Hospital, UKSearch for more papers by this author J. Lear, J. Lear departments of Dermatology, North Staffordshire Hospital and Royal Cornwall HospitalsSearch for more papers by this authorA. Heagerty, A. Heagerty departments of Dermatology, North Staffordshire Hospital and Royal Cornwall HospitalsSearch for more papers by this authorA. Smith, A. Smith departments of Dermatology, North Staffordshire Hospital and Royal Cornwall HospitalsSearch for more papers by this authorB. Bowers, B. Bowers departments of Dermatology, North Staffordshire Hospital and Royal Cornwall HospitalsSearch for more papers by this authorP. Jones, P. Jones department of Mathematics, Keele UniversitySearch for more papers by this authorJ. Gilford, J. Gilford Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, North Staffordshire Hospital, UKSearch for more papers by this authorJ. Alldersea, J. Alldersea Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, North Staffordshire Hospital, UKSearch for more papers by this authorA. Fryer, A. Fryer Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, North Staffordshire Hospital, UKSearch for more papers by this authorR. Strange, R. Strange Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, North Staffordshire Hospital, UKSearch for more papers by this author First published: April 1996 https://doi.org/10.1111/j.1751-1097.1996.tb03062.xCitations: 6AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 Farndon, P. A., R. G. Mastro, D. G. Evans and M. W. Kilpatrick (1992) Location of gene for Gorlin syndrome. Lancet 339, 581– 582. 2 Smith, G., L. A. Stanley, E. Sim, R. C. Strange and C. R. Wolf (1995) Metabolic polymorphisms and cancer susceptibility. Cancer Surv. 25, 27– 65. 3 Kricker, A., B. K. Armstrong, M. E. Jones and R. C. Burton (1993) Health, Solar UV Radiation and Environmental Change, pp. 52– 61. International Agency for Research on Cancer, Technical Report no. 13, Lyon. 4 Karagas, M. R. and E. R. Greenberg (1995) Unresolved issues in the epidemiology of basal cell and squamous cell skin cancer. In Skin Cancer: Mechanisms and Human Relevance (Edited by H. Mukhtar), pp. 79– 86. CRC Press, Boca Raton , FL . 5 Fitzpatrick, T. B. (1988) The validity and practicality of sun reaction skin types I through VI. Arch. Dermatol. 124, 869– 871. 6 Kripke, M. L. (1994) Ultraviolet radiation and immunology: something new under the sun. Cancer Res. 54, 6102– 6105. 7 Wei, Q., G. Mutanoski, E. R. Farmer, M. A. Hedayati and L. Grossman (1994) DNA repair related to multiple skin cancers and drug use. Cancer Res. 54, 437– 440. 8 Black, H. S. (1987) Potential involvement of free radical reactions in ultraviolet light-mediated cutaneous damage. Photo-chem. Photobiol. 46, 213– 221. 9 Touati, D. (1989) The molecular genetics of superoxide dis-mutase in E. coli. An approach to understanding the biological role and regulation of SODs in relation to other elements of the defence system against oxygen toxicity. Free Radical Res. Com-mun. 8, 1– 9. 10 Halliwell, B. and O. I. Aruoma (1991) DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS Lett. 281, 9– 19. 11 Hayes, J. D. and R. C. Strange (1995) Potential contribution of the glutathione S-transferase supergene family to resistance to oxidative stress. Free Radical Res. Commun. 22, 193– 207. 12 Ketterer, B., J. Taylor, D. Meyer, S. Pemble, B. Coles, X. ChuLin and S. Spencer (1993) Some functions of glutathione transferases. In Structure and Function of Glutathione Transferases (Edited by K. Tew, B. Mannervik, T. J. Mantle, C. B. Pickett and J. D. Hayes), pp. 15– 27. CRC Press, Boca Raton , FL . 13 Strange, R. C. (1995) Glutathione 5-transferases and cancer susceptibility. In Proceedings 1995 International ISSX Workshop on Glutathione S-Transferases Taylor and Francis. (In press). 14 Pemble, S., K. R. Schroeder, S. R. Spencer, D. J. Meyer, E. Hallier, H. M. Bolt, B. Ketterer and J. B. Taylor (1994) Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterisation of a genetic polymorphism. Biochem. J. 300, 271– 276. 15 Heagerty, A. H. M., D. Fitzgerald, A. Smith, B. Bowers, P. Jones, A. A. Fryer, L. Zhao, J. Alldersea and R. C. Strange (1994) Glutathione 5-transferase GSTM1 phenotypes and protection against cutaneous malignancy. Lancet 343, 266– 268. 16 Heagerty, A., A. Smith, J. English, J. Lear, W. Perkins, B. Bowers, P. Jones, J. Gilford, J. Alldersea, A. A. Fryer and R. C. Strange (1995) Susceptibility to multiple cutaneous basal cell carcinomas: significant interactions between glutathione 5-transferase GSTM1 genotypes, skin type and male gender. Br. J. Cancer. 73, 44– 48. 17 Nakachi, K., K. Imai, S. Hayashi and K. Kawajiri (1993) Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. Cancer Res. 53, 2994– 2999. 18 McHenry, P. M., T. Aitchison and R. M. Mackie (1996) Comparison of risk factors for lentigo maligna melanoma, basal cell carcinoma and squamous cell carcinoma. Scot. J. Med (In press). 19 Nebert, D. W. (1994) Drug-metabolizing enzymes in ligand-modulated transcription. Biochem. Pharmacol. 47, 25– 37. 20 Jugert, F. K., R. Agarwal, A. Kuhn, D. R. Bickers, H. F. Merk and H. Mukhtar (1994) Multiple cytochrome P450 isoenzymes in murine skin: induction of P4501A, 2B, 2E and 3A by dexa-methasone. J. Invest. Dermatol. 102, 970– 975. 21 Wolf, C. R., C. A. D. Smith, A. C. Gough, J. E. Moss, K. A. Vallis, G. Howard, F. J. Carey, K. Mills, W. McNee, J. Car-michael and N. K. Spurr (1992) Relationship between the de-brisoquine polymorphism and cancer susceptibility. Carcinogenesis 13, 1035– 1038. 22 Yeh, S., S. W. How and C. J. Lin (1968) Arsenical cancer of skin. Histologic study with special reference to Bowen's disease. Cancer 21, 312– 319. 23 Ryberg, D., E. Kure, S. Lystad, V. Skaug, L. Stangeland, I. Mercy, A.-L. Bfrresen and A. Haugen (1994) p53 mutations in lung tumours: relationship to putative susceptibility markers for cancer. Cancer Res. 54, 1551– 1555. 24 Perrett, C. W., R. N. Clayton, M. Pistorello, M. Boscaro, M. Scanarini, A. Bates, N. Buckley, P. Jones, A. A. Fryer, J. Gilford, J. Alldersea and R. C. Strange (1995) GSTM1 and CYP2D6 genotype frequencies in patients with pituitary tumours: effects on P53, RAS and GSP. Carcinogenesis 16, 1643– 1645. Citing Literature Volume63, Issue4April 1996Pages 424-428 ReferencesRelatedInformation