Artigo Produção Nacional Revisado por pares

Hepatitis B serological patterns of asymptomatic carriers in an endemic region and evaluation of blood plasma as a source of hepatitis B vaccine

1986; Elsevier BV; Volume: 4; Issue: 4 Linguagem: Inglês

10.1016/0264-410x(86)90140-4

ISSN

1873-2518

Autores

Clara Fumiko Tachibana Yoshida, I. F. Camargo, L. A. C. Mercadante, Ana Gaspar, D.F.D.L. Gomes, H. G. Schatzmayr,

Tópico(s)

Enzyme Production and Characterization

Resumo

Hepatitis B serological studies were carried out in 251 asymptomatic carriers of HBsAg living in an endemic rural area of Cachoeiro do Itapemirim (545 km distant from Rio de Janeiro) in order to evaluate this population as a potential source of blood plasma for hepatitis B vaccine production. A pilot study on HBsAg purification from plasma was also performed to estimate antigen yield.

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