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A fluorescein-derived anthocyanidin-inspired pH sensor

2009; Elsevier BV; Volume: 50; Issue: 26 Linguagem: Inglês

10.1016/j.tetlet.2009.03.223

1873-3581

Asier Unciti‐Broceta, Muhammad Rahimi Yusop, P. Richardson, Jeffrey G. A. Walton, Mark Bradley,

Luminescence and Fluorescent Materials

A new multicolor pH-dependent fluorophore was synthesized via Pd-mediated cross-coupling chemistry of the mono-triflate of fluorescein with p-hydroxyphenylboronic acid. The novel indicator, named anthofluorescein, is highly sensitive to pH changes between 7 and 10 and displays a green to red fluorescence shift, making it a valuable candidate for biological studies.