Cyclic Voltammetry of Two Analogue K-Group Vitamin Compounds in Dimethylsulfoxide
1998; Wiley; Volume: 10; Issue: 9 Linguagem: Inglês
10.1002/(sici)1521-4109(199807)10
ISSN1521-4109
Autores Tópico(s)Vitamin C and Antioxidants Research
ResumoThe electrochemical reduction of two analogue K-group vitamin compounds, menadione and phthiocol, was studied by cyclic voltammetry in DMSO on glassy carbon electrodes. The reduction process of the more biologically active of these compounds (menadione), is associated with the formation of the semiquinone anion radical and the dianion. Two separated reversible one-electron peaks were observed. In contrast, the less biologically active phthiocol exhibits a single irreversible 2/3-electron peak which is explained by an ECE-DISP1 self-protonation mechanism. In the presence of a donor proton such as benzoic acid, menadione and phthiocol are reduced both through a sequence of consecutive electron transfer and protonation reactions occurring via an irreversible two-electron ECE-DISP1 mechanism.
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