Portal de Periódicos da CAPES

Partial monosomy of distal 10q: Three new cases and a review

1999; Wiley; Volume: 86; Issue: 1 Linguagem: Inglês

10.1002/(sici)1096-8628(19990903)86

1096-8628

Darrel Waggoner, Clara K Chow, S. Bruce Dowton, Michael S. Watson,

Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

We report on 3 patients with partial deletions of the long arm of chromosome 10-46,XY,del (10)(q26.2), 46,XX,del(10) (q25.3q26.3) or 46,XX,del(10)(q26.1), and 46,XX,del (10)(q26.1). They are compared with other known cases with interstitial or terminal deletions involving chromosome bands 10q25 or q26. Unique manifestations are identified, including scoliosis and a severe behavior disorder with attention deficit and hyperactivity in a 12-year-old boy as well as patchy alopecia in a 6-year-old patient.