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Serotonin Neurotransmission in Cocaine Sensitizationa

1992; Wiley; Volume: 654; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1992.tb25960.x

1749-6632

Kathryn A. Cunningham, Joseph M. Paris, Nick E. Goeders,

Neuroscience and Neuropharmacology Research

Annals of the New York Academy of SciencesVolume 654, Issue 1 p. 117-127 Serotonin Neurotransmission in Cocaine Sensitizationa KATHRYN A. CUNNINGHAM, Corresponding Author KATHRYN A. CUNNINGHAM Department of Pharmacology and Toxicology University of Texas Medical Branch Galveston, Texas 77550Author to whom all correspondence should be addressed; Tel.: (409) 772-9629.Search for more papers by this authorJOSEPH M. PARIS, JOSEPH M. PARIS Department of Pharmacology and Toxicology University of Texas Medical Branch Galveston, Texas 77550Search for more papers by this authorNICK E. GOEDERS, NICK E. GOEDERS Department of Pharmacology and Therapeutics Louisiana State University School of Medicine Shreveport, Louisiana 71130Search for more papers by this author KATHRYN A. CUNNINGHAM, Corresponding Author KATHRYN A. CUNNINGHAM Department of Pharmacology and Toxicology University of Texas Medical Branch Galveston, Texas 77550Author to whom all correspondence should be addressed; Tel.: (409) 772-9629.Search for more papers by this authorJOSEPH M. PARIS, JOSEPH M. PARIS Department of Pharmacology and Toxicology University of Texas Medical Branch Galveston, Texas 77550Search for more papers by this authorNICK E. GOEDERS, NICK E. GOEDERS Department of Pharmacology and Therapeutics Louisiana State University School of Medicine Shreveport, Louisiana 71130Search for more papers by this author First published: June 1992 https://doi.org/10.1111/j.1749-6632.1992.tb25960.xCitations: 31 a This work was supported by the National Alliance for Schizophrenia and Affective Disorders and USPHS Grants DA 05708 and DA 06511 (KAC), DA 05381 (JMP) and DA 04293 (NEG) from the National Institute on Drug Abuse (NIDA). 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J. Pharmacol. 159: 157– 164. 4 Scheel-Kruger, J., C. Braestrup, M. Nielson, K. Golembiowska & E. Mogilnicka 1976. Cocaine: Discussion on the role of dopamine in the biochemical mechanism of action. In Cocaine and Other Stimulants. E. H. Ellinwood & M. M. Kilbey, Eds.: 373– 407. Plenum Press. New York . 5 Roberts, D. C. S., M. E. Corcoran & H. C. Fibiger 1977. On the role of ascending catecholamine systems in intravenous self-administration of cocaine. Pharmacol. Biochem. Behav. 6: 615– 620. 6 de Wit, H. & R. A. Wise 1977. Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine. Can. J. Psychol. 31: 195– 203. 7 Callahan, P. M., J. B. Appel & K. A. Cunningham 1991. Dopamine D1 and D2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine. Psychopharmacology 103: 50– 55. 8 Colpaert, F. C., C. J. E. Niemegeers & P. A. J. Janssen 1979. Discriminative stimulus properties of cocaine: Neuropharmacological characteristics as derived from stimulus generalization experiments. Pharmacol. Biochem. Behav. 10: 535– 546. 9 Cunningham, K. A. & J. B. Appel 1982. Discriminative stimulus properties of cocaine and phencyclidine: Similarities in mechanism of action. In Drug Discrimination: Applications in CNS Pharmacology. F. C. Colpaert & J. L. Slangen, Eds.: 181– 192. Elsevier/North Holland Biomedical Press. Amsterdam . 10 Cunningham, K. A. & P. M. Callahan 1991. Monoamine reuptake inhibitors potentiate the discriminative state induced by cocaine in the rat. Psychopharmacology 104: 177– 180. 11 Gale, K. 1984. Catecholamine-independent behavioral and neurochemical effects of cocaine in rats. In Mechanisms of Tolerance and Dependence, NIDA Monograph 54. C. W. Sharp, Ed.: 323– 332. U. S. Government Printing Office, Washington , D.C. . 12 Spyraki, C., H. C. Fibiger & A. G. Phillips 1982. Cocaine-induced place preference conditioning: Lack of effects of neuroleptics and 6-hydroxydopamine lesions. Brain Res. 253: 195– 203. 13 Knapp, S. & A. J. Mandell 1972. Narcotic drugs: Effects on the serotonin biosynthetic systems of the brain. Science 177: 1209– 1211. 14 Galloway, M. P. 1990. Regulation of dopamine and serotonin synthesis by acute administration of cocaine. Synapse 6: 63– 72. 15 Reith, M. E. A., H. Sershen, D. L. Allen & A. Lajtha 1983. A portion of 3H-cocaine binding in brain is associated with serotonergic neurons. Mol. Pharmacol. 23: 600– 606. 16 Fozard, J. R., A. T. M. Mobarok Ali & G. Newgrosh 1979. Blockade of serotonin receptors on autonomic neurones by (-)-cocaine and some related compounds. Eur. J. Pharmacol. 59: 195– 210. 17 Costall, B., A. M. Domeney, R. J. Naylor & M. B. Tyers 1987. Effects of the 5-HT3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain. Br. J. Pharmacol. 92: 881– 894. 18 Paris, J. M. & K. A. Cunningham 1991. Serotonin 5-HT3 antagonists do not alter the discriminative stimulus properties of cocaine. Psychopharmacology 104: 475– 478. 19 Peltier, R. & S. Schenk 1991. GR38032F, a serotonin 5-HT3 antagonist, fails to alter cocaine self-administration in rats. Pharmacol. Biochem. Behav. 39: 133– 136. 20 van DER Hoek, G. A. & S. J. Cooper 1990. Evidence that ondansetron, a selective 5-HT3 antagonist, reduces cocaine's psychomotor stimulant effects in the rat. Psychopharmacology 101: S59. 21 Pradhan, S. N., A. K. Battacharyya & S. Pradhan 1978. Serotonergic manipulation of the behavioral effects of cocaine in rats. Commun. Psychopharmacol. 2: 481– 486. 22 Steinbusch, H. W. M. 1984. 3: Serotonin-immunoreactive neurons and their projections in the CNS. In Handbook of Chemical Neuroanatomy: Classical Transmitters and Transmitter Receptors in the CNS. A. BjoUrklund, T. Hökfelt & M. J. Kuhar, Eds.: 68– 125. Elsevier Science Publishers. Amsterdam . 23 Gobbi, M., L. Cervo, C. Taddei & T. Mennini 1990. Autoradiographic localization of [3H]paroxetine specific binding in the rat brain. Neurochem. Int. 16: 247– 251. 24 Radja, F., A.-M. Laporte, G. Daval, D. Verge, H. Gozlan, M. Hamon, J. M. Palacios, C. Waeber, G. Mengod & D. Hoyer 1991. Autoradiography of serotonin receptor subtypes in the central nervous system. Neurochem. Int. 18: 1– 15. 25 Sprouse, J. S. & G. K. Aghajanian 1987. Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists. Synapse 1: 3– 9. 26 Cunningham, K. A. & J. M. Lakoski 1988. Electrophysiological effects of cocaine and procaine on dorsal raphe serotonin neurons. Eur. J. Pharmacol. 148: 457– 462. 27 Cunningham, K. A. & J. M. Lakoski 1990. The interaction of cocaine with serotonin dorsal raphe neurons: Single unit extracellular recording studies. Neuropsychopharmacology 3: 41– 50. 28 Pitts, D. K. & J. Marwah 1987. Cocaine modulation of central monoaminergic neurotransmission. Pharmacol. Biochem. Behav. 26: 453– 461. 29 Einhorn, L. C., P. A. Johansen & F. J. White 1988. Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: Studies in the ventral tegmental area. J. Neurosci. 8: 100– 112. 30 Pitts, D. K. & J. Marwah 1987. Electrophysiological actions of cocaine on noradrenergic neurons in rat locus coeruleus. J. Pharmacol. Exp. Ther. 240: 345– 351. 31 Nyback, H. V., J. R. Walters, G. K. Aghajanian & R. H. Roth 1975. Tricyclic antidepressants: Effects on the firing rate of noradrenergic neurons. Eur. J. Pharmacol. 32: 302– 312. 32 Lum, J. R. & M. F. Piercey 1988. Electrophysiological evidence that spiperone is an antagonist of 5-HT1A receptors in the dorsal raphe nucleus. Eur. J. Pharmacol. 149: 9– 15. 33 Lowenstein, D. H., S. M. Massa, M. C. Rowbotham, S. D. Collins, H. E. McKinney & R. P. Simon 1987. Acute neurologic and psychiatric complications associated with cocaine abuse. Am. J. Med. 83: 841– 846. 34 Post, R. M. 1975. Cocaine psychoses: A continuum model. Am. J. Psychiatry 132: 225– 230. 35 Post, R. M., S. R. B. Weiss, A. Pert & T. W. Uhde 1987. Chronic cocaine administration: Sensitization and kindling effects. In Cocaine: Clinical and Biobehavioral Aspects. S. Fisher, A. Raskin & E. H. Uhlenhuth, Eds.: 109– 173. Oxford University Press. New York . 36 Robinson, T. E. & J. B. Becker 1986. Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis. Brain Res. Rev. 11: 157– 198. 37 Peris, J., S. J. Boyson, W. A. Cass, P. Curella, L. P. Dwoskin, G. Larson, L.-H. Lin, R. P. Yasuda & N. R. Zahniser 1990. Persistence of neurochemical changes in dopamine systems after repeated cocaine administration. J. Pharmacol. Exp. Ther. 253: 38– 44. 38 Pettit, H. O., H.-T. Pan, L. H. Parsons & J. B. Justice, Jr. 1990. Extracellular concentrations of cocaine and dopamine are enhanced during chronic cocaine administration. J. Neurochem. 55: 798– 804. 39 Yi, S. J. & K. M. Johnson 1990. Effects of acute and chronic administration of cocaine on striatal uptake, compartmentalization and release [3H]dopamine. Neuropharmacology 29: 475– 486. 40 Goeders, N. E. & M. J. Kuhar 1987. Chronic cocaine administration induces opposite changes in dopamine receptors in the striatum and nucleus accumbens. Alc. Drug Res. 7: 207– 216. 41 Kleven, M. S., B. D. Perry, W. L. Woolverton & L. S. Seiden 1990. Effects of repeated injections of cocaine on D1 and D2 dopamine receptors in rat brain. Brain Res. 532: 265– 270. 42 Henry, D. J., M. A. Greene & F. J. White 1989. Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: Repeated administration. J. Pharmacol. Exp. Ther. 251: 833– 839. 43 Henry, D. J. & F. J. White 1989. Effects of repeated cocaine administration on the sensitivity of D1 and D2 receptors in the nucleus accumbens. Soc. Neurosci. Abst. 15: 1013. 44 Cunningham, K. A. 1988. Cocaine: Behavioral sensitization and the serotonin syndrome. Soc. Neurosci. Abst. 14: 659. 45 Karler, R., L. D. Calder & S. A. Turkanis 1990. Reverse tolerance to amphetamine evokes reverse tolerance to 5-hydroxytryptophan. Life Sci. 46: 1773– 1780. 46 Cunningham, K. A., J. M. Paris & N. E. Goeders Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding. Synapse. In press. 47 Kilbey, M. M. & E. H. Ellinwood 1976. Chronic administration of stimulant drugs: Response modification. In Cocaine and Other Stimulants. E. H. Ellinwood & M. M. Kilbey, Eds.: 409– 429. Plenum Press. New York . 48 Paris, J. M., P. M. Callahan, J. M. Lee & K. A. Cunningham 1991. Behavioral sensitization to cocaine is not associated with changes in serotonin (5-HT) immunoreactivity in rat forebrain. Brain Res. Bull. 27: 843– 847. 49 Delfs, J. M., L. Schreiber & A. E. Kelley 1990. Microinjection of cocaine into the nucleus accumbens elicits locomotor activation in the rat. J. Neurosci. 10: 303– 310. 50 Goeders, N. E. & J. E. Smith 1983. cortical dopaminergic involvement in cocaine reinforcement. Science 221: 773– 775. 51 Conway, P. G. & D. J. Brunswick 1985. High- and low-affinity binding components for [3H]imipramine in rat cerebral cortex. J. Neurochem. 45: 206– 209. 52 Hrdina, P. D. 1987. Regulation of high- and low-affinity [3H]imipramine recognition sites in rat brain by chronic treatment with antidepressants. Eur. J. Pharmacol. 138: 159– 168. 53 Kleven, M. S., W. L. Woolverton & L. S. Seiden 1988. Lack of long-term monoamine depletions following repeated or continuous exposure to cocaine. Brain Res. Bull. 21: 233– 237. 54 Yeh, S. Y. & E. B. De Souza 1991. Lack of neurochemical evidence for neurotoxic effects of repeated cocaine administration in rats on brain monoamine neurons. Drug Alcohol Depend. 27: 51– 61. 55 Blier, P., C. de Montigny & D. Tardif 1984. Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: Single-cell studies in the rat. Psychopharmacology 84: 242– 249. 56 Blier, P., Y. Chaput & C. de Montigny 1988. Long-term 5-HT reuptake blockade, but not monoamine oxidase inhibition, decreases the function of terminal 5-HT autoreceptors: An electrophysiological study in the rat brain. Naunyn-Schmiedeberg's Arch. Pharmacol. 337: 246– 254. 57 Brunello, N., M. Riva, A. Volterra & G. Racagni 1987. Effect of some tricyclic and nontricyclic antidepressants on [3H]imipramine binding and serotonin uptake in rat cerebral cortex after prolonged treatment. Fundam. & Clin. Pharmacol. 1: 327– 333. 58 Chaput, Y., C. de Montigny & P. Blier 1986. Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: Electrophysiological studies in the rat brain. Naunyn-Schmiedeberg's Arch. Pharmacol. 333: 342– 348. 59 Montero, D., M. L. De Ceballos & J. Del-Rio 1990. Down-regulation of [3H]imipramine binding sites in rat cerebral cortex after prenatal exposure to antidepressants. Life Sci. 46: 1619– 1626. 60 Hillegaart, V., S. Hjorth & S. Ahlenius 1990. Effects of 5-HT and 8-OHDPAT on forebrain monoamine synthesis after local application into the median and dorsal raphe nuclei of the rat. J. Neural Transm. 81: 131– 145. 61 Mantz, J., R. Godbout, J.-P. Tassin, J. Glowinski & A.-M. Thierry 1990. Inhibition of spontaneous and evoked unit activity in the rat medial prefrontal cortex by mesencephalic raphe nuclei. Brain Res. 524: 22– 30. 62 Sharp, T., S. R. Bramwell, D. Clark & D. G. Grahame-Smith 1989. In vivo measurement of extracellular 5-hydroxytryptamine in hippocampus of the anaesthetized rat using microdialysis: Changes in relation to 5-hydroxytryptaminergic neuronal activity. J. Neurochem. 53: 234– 240. 63 Wang, R. Y. & G. K. Aghajanian 1977. Inhibition of the neurons of the amygdala by dorsal raphe stimulation: Mediation through direct serotonergic pathway. Brain Res. 120: 85– 102. 64 White, F. J. 1986. Comparative effects of LSD and lisuride: Clues to specific hallucinogenic drug actions. Pharmacol. Biochem. Behav. 24: 365– 379. 65 Fibiger, H. C. & J. J. Miller 1977. An anatomical and electrophysiological investigation of the serotonergic projection from the dorsal raphe nucleus to the substantia nigra in the rat. Neuro Science 2: 975– 987. 66 Moore, R. Y., A. E. Halaris & B. E. Jones 1978. Serotonin neurons of the midbrain raphe: Ascending projections. J. Comp. Neurol. 180: 417– 438. 67 Kalivas, P. W. & P. Duffy 1988. Effects of daily cocaine and morphine treatment on somatodendritic and terminal field dopamine release. J. Neurochem. 50: 1498– 1504. 68 Thierry, A. M., J. P. Tassin, G. Blanc & J. Glowinski 1976. Selective activation of the mesocortical dopaminergic system by stress. Nature 263: 242– 244. 69 Isaac, W. L., A. J. Nonneman, J. Neisewander, T. Landers & M. T. Bardo 1989. Prefrontal cortical lesions differentially disrupt cocaine-reinforced conditioned place preference but not conditioned taste aversion. Behav. Neurosci. 103: 345– 355. 70 Anthony, J. C., A. Y. Tien & K. R. Petronis 1989. Epidemiologic evidence on cocaine use and panic attacks. Am. J. Epidemiology 129: 543– 549. 71 Aronson, T. A. & T. J. Craig 1986. Cocaine precipitation of panic disorder. Am. J. Psychiatry 143: 643– 645. 72 Loh, E. A. & D. C. S. Roberts 1990. Break points on a progressive ratio schedule re-inforced by intravenous cocaine increase following depletion of forebrain serotonin. Psychopharmacology 101: 262– 266. 73 Carroll, M. E., S. T. Lac, M. Asencio & R. Kragh 1990. Fluoxetine reduces intravenous cocaine self-administration in rats. Pharmacol. Biochem. Behav. 35: 237– 244. 74 Carroll, M. E., S. T. Lac, M. Asencio & R. Kragh 1990. Intravenous cocaine self-administration in rats is reduced by dietary l-tryptophan. Psychopharmacology 100: 293– 300. Citing Literature Volume654, Issue1The Neurobiology of Drug and Alcohol AddictionJune 1992Pages 117-127 ReferencesRelatedInformation