Intracardiac right-to-left shunting following cardiac surgery
1988; Elsevier BV; Volume: 116; Issue: 1 Linguagem: Inglês
10.1016/0002-8703(88)90268-2
ISSN1097-6744
AutoresJames I. Klepper, F. Seifert, William E. Lawson, George I. Mallis, John Dervan, Gerald C. Smaldone, Edward J. Brown,
Tópico(s)Cardiovascular Effects of Exercise
ResumoThe cause of right-to-left atrial shunting despite normal intracardiac pressures and normal or near-normal pulmonary function through a patent foramen ovale has still not been completely clarified. It is probably responsible for several linked diseases, such as paradoxical embolism, platypnea-orthodeoxia syndrome, migraine with aura, transient global amnesia, and decompression sickness in sport divers. Despite modern diagnostic methods, the underlying anatomophysiologic and pathogenic mechanisms of right-to-left atrial shunting without abnormal intracardiac pressures remain a matter of debate and controversy. Holistically speaking, a return to a direct study of embryology, gross anatomy, and physiology may help us elucidate the real mechanism of this paradoxical shunting
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