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The Nephrotic Syndrome in Secondary Syphilis

1965; American College of Physicians; Volume: 63; Issue: 6 Linguagem: Inglês

10.7326/0003-4819-63-6-1047

1539-3704

W. Fred Falls,

Syphilis Diagnosis and Treatment

Case Studies1 December 1965The Nephrotic Syndrome in Secondary SyphilisReport of a Case with Renal Biopsy FindingsWILLIAM F. FALLS JR., M.D., KENNETH L. FORD, M.D., CHARLES T. ASHWORTH, M.D., NORMAN W. CARTER, M.D.WILLIAM F. FALLS JR., M.D.Search for more papers by this author, KENNETH L. FORD, M.D.Search for more papers by this author, CHARLES T. ASHWORTH, M.D.Search for more papers by this author, NORMAN W. CARTER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-6-1047 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSeveral cases of the nephrotic syndrome associated with active syphilitic infection have been reported in the past (1-16). Because of the self-limited nature of this illness, however, there have been few reports containing histologic descriptions of the kidney during the active phase of the nephrotic syndrome. Robins and Ladd (13) reported a case in 1962 in which they included descriptions of two renal biopsies. One biopsy was taken during the active phase of the disease, but after the initiation of therapy, and the other was obtained 1 month later. These authors stated that in their case there were no glomerular...References1. BAKER BM: The relation of syphilis to nephritis. Bull. Hopkins Hosp. 65: 196, 1931. Google Scholar2. BARRCOLEDRIVERLEASMILLERSTRAUSS JHHNJRRDMLG: Acute syphilitic nephrosis successfully treated with penicillin. JAMA 131: 741, 1964. Google Scholar3. BROPHYASHWORTHARIASREYNOLDS EMCTMJ: Acute syphilitic nephrosis in pregnancy. Obstet. Gynec. 24: 930, 1964. Google Scholar4. COOKWARSHAWSKY HDH: Acute syphilitic nephrosis. Amer. Practit. 3: 129, 1948. Google Scholar5. FURMANGALEORYWEINSTEIN RHRGEMA: Renal function studies in acute syphilitic nephrosis before and after treatment with penicillin. Ann. Intern. Med. 35: 444, 1951. LinkGoogle Scholar6. 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Med. 115, 421, 1962. CrossrefMedlineGoogle Scholar42. FELDMANFISHER JDER: Renal lesions of aminonucleoside nephrosis. Lab. Invest. 8: 371, 1959. MedlineGoogle Scholar43. MOVATSTEINERSLATER HZJWRJ: The fine structure of the glomerulus in Bright's disease: a clinicopathological study, in Renal Biopsy, CIBA Foundation Symposium, Little, Brown and Co., Boston, 1961, pp. 103-136. CrossrefGoogle Scholar44. PIRANIPOLLAKMUEHRCKEKARK CLVERCRM: Lupus nephritis, in Renal Biopsy, CIBA Foundation Symposium, Little, Brown and Co., Boston, 1961, pp. 218-241. CrossrefGoogle Scholar45. SPARGOARNOLD BJD: Glomerular extrinsic membranous deposit with the nephrotic syndrome. Ann. N. Y. Acad. Sci. 86: 1043, 1960. CrossrefGoogle Scholar46. MAUTNERCHURGGRISHMANDACHS WJES: Preeclamptic nephropathy: an electron microscopic study. Lab. Invest. 11: 518, 1962. MedlineGoogle Scholar47. HOPPERFARQUHARYAMAUCHIMOONPAGE JMGHHDEW: Renal lesions in pregnancy. Clinical observations and light and electron microscopic findings. Obstet. Gynec. 17: 271, 1961. Google Scholar48. FELDMAN JD: Electron microscopy of serum sickness nephritis. J. Exp. Med. 108: 957, 1958. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Dallas, TexasFrom the Department of Internal Medicine and Pathology, University of Texas Southwestern Medical School, Dallas, Tex.Dr. Carter was supported in part by grant HE-0876, U. S. Public Health Service, Bethesda, Md.Dr. Falls is a trainee under grant 5 T1 AM 5028 from the United States Public Health Service, Bethesda, Md., and Dr. Ford is a trainee under grant GM-227 from the United States Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Norman W. Carter, M.D., Department of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Tex. 75235. 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A case report.The Role of Fatty Acid Oxidation in The EpidermisDemonstration by Labeled Treponemal Antigen of Specific Antibodies in The Tissue Infiltrates of Secondary SyphilisMembranous glomerulonephritis mediated by renal tubular epithelial antigen-antibody complexCorrespondence: An attempt to produce immune complexes in experimental syphilis.Membranous glomerulonephritis: Long-term serial observations on clinical course and morphologyNephrotic syndrome in congenital syphilis.Membranous glomerulonephritis: Current statusThe nephrotic syndrome associated with secondary syphilisULTRASTRUCTURAL PATHOLOGY OF THE TUBULES AND INTERSTITIAL TISSUE 1 December 1965Volume 63, Issue 6Page: 1047-1058KeywordsBiopsyElectron microscopyFallsKidneysLesionsMedical servicesProteinuriaSyphilis Issue Published: 1 December 1965 PDF DownloadLoading ...