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Changes in the Sulfhydryl and Disulfide Groups in Animal Skin Following a Single Exposure to Ultraviolet Light

1962; Elsevier BV; Volume: 39; Issue: 4 Linguagem: Inglês

10.1038/jid.1962.114

1523-1747

Masakazu Kusuhara, John M. Knox,

Skin Protection and Aging

In studies relating to melanin formation it has been shown that there is an inhibition in vitro of the tyrosine-tyrosinase reaction by extracts of human epidermis. This inhibition has been attributed to the presence of sulfhydryl groups. (1,2). After irradiation of epidermal extracts with ultraviolet light this inhibitory action was absent, presumably because ultraviolet light causes a decrease in the concentration of sulfhydryl groups of the human epidermis (2).