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Feo-hifomicose subcutânea por Exophiala jeanselmei: registro de três casos em transplantados renais

1994; UNIVERSIDADE DE SÃO PAULO; Volume: 36; Issue: 2 Linguagem: Inglês

10.1590/s0036-46651994000200015

ISSN

1678-9946

Autores

E Sabbaga, Leontina Margarido Tedesco-Marchesi, Carlos da Silva Lacaz, Luiz Carlos Cucé, A Salebian, Elisabeth Maria Heins‐Vaccari, Mírian Nacagami Sotto, Neusa Yuriko Sakai Valente, Edward Porto, Maurício Levy‐Neto,

Tópico(s)

Infections and bacterial resistance

Resumo

We report three cases of subcutaneous phaeohyphomycosis due to Exophiala jeanselmei (Langeron) McGinnis et Padhye 1977, in kidney transplant patients. Exophiala jeanselmei is a dematious fungus having also ability to rarely procedure eumycetoma (black grains). According to KWON-CHUNG & BENNETT (1992) such fungus is antigenically very heterogeneous, since so far three serotypes have been identified; each serotype including subgroups. Subcutaneous phaeohyphomycosis is becoming more and more frequent in kidney transplant patients submitted to an immunosuppressive treatment. As Exophiala jeanselmei has already been isolated from the environment it becomes difficult to explain the pathogenicity of these cases by a reactivation of quiescent processes. The authors suggest an occasional fungistatic action of cyclosporine A upon Exophiala jeanselmei.

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