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Avaliação prospectiva da ocorrência de infecção em pacientes críticos de unidade de terapia intensiva

2007; Associação de Medicina Intensiva Brasileira; Volume: 19; Issue: 3 Linguagem: Inglês

10.1590/s0103-507x2007000300013

ISSN

1982-4335

Autores

Mery Ellen Lima, Denise de Andrade, Vanderlei José Haas,

Tópico(s)

Nosocomial Infections in ICU

Resumo

Care in the intensive care unit (ICU) is constantly challenged by infections related to invasive procedures, which result in increased morbidity and mortality, hospitalization term and costs. This study aimed to prospectively evaluate critical patients according to age, clinical conditions, hospitalization term, occurrence of hospital infection, topography of hospital infection, occurrence of microbial multi-resistance or not, use of invasive procedures and antimicrobial agents.This is a prospective, observational, clinical research, carried out at an ICU between February and July 2006. The research subjects were critical patients hospitalized for more than 24 hours at the ICU, followed from admission until discharge, transference or death.The study group consisted of 71 patients with a mean age of 53.5 ± 18.75 years. Forty-seven of these patients (66.2%) acquired hospital infection. Twenty-nine infections (37.6%) occurred in the blood stream, 20 (26%) respiratory and 13 (16.9%) urinary. The most frequent multi-resistant strains were: 14 (10.85%) Pseudomonas aeruginosa, 4 (3.1%) coagulase-negative Staphylococcus sp and 4 (3.1%) Staphylococcus aureus. The most used antimicrobial agents were carbapenem (22.4%), glycopeptides (21.6%) and cephalosporin (21.6%). Twenty-nine (40.8%) of these patients died.Hospital infection is aggravated if associated to the increased resistance of the microorganisms to the antibiotics.

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