Antifeedant Activity of Withanolides from Salpichroa o riganifolia on Musca d omestica
2000; American Chemical Society; Volume: 63; Issue: 8 Linguagem: Inglês
10.1021/np0001068
ISSN1520-6025
AutoresGraciela Mareggiani, María Inés Picollo, Eduardo Zerba, Gerardo Burton, M. Cristina Tettamanzi, Miriam O. V. Benedetti-Doctorovich, Adriana S. Veleiro,
Tópico(s)Complementary and Alternative Medicine Studies
ResumoThe antifeedant effect of several salpichrolides on larvae of Musca domestica was investigated. Three naturally occurring compounds, salpichrolide A (1), salpichrolide C (2), and salpichrolide G (3), previously isolated from Salpichroa origanifolia, and two known (4, 6) and three new (5, 7, 8) synthetic analogues were tested. The maximal effect on development was observed for salpichrolide A (1), while salpichrolide G (3) was the most toxic. The content of the salpichrolides in S. origanifolia was monitored by HPLC during plant development, reaching a maximum during summer.
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