Highly Diastereo- and Enantioselective Reagents for Aldehyde Crotylation
2004; American Chemical Society; Volume: 6; Issue: 23 Linguagem: Inglês
10.1021/ol0480731
ISSN1523-7060
AutoresBlaine M. Hackman, Pamela J. Lombardi, James L. Leighton,
Tópico(s)Asymmetric Synthesis and Catalysis
ResumoTwo new, crystalline solid, storable, and highly enantioselective reagents for aldehyde crotylation have been developed. Both (cis and trans) crotylsilane reagents are easily prepared in bulk, require trivial reaction conditions, and provide the homoallylic alcohol products with near diastereo- and enantiospecificity in many cases.
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