Analysis of antiarrhythmic drug concentrations determined during electrophysiologic drug testing in patients with inducible tachycardias
1988; Elsevier BV; Volume: 61; Issue: 11 Linguagem: Inglês
10.1016/0002-9149(88)90376-1
ISSN1879-1913
AutoresNada S. Berry, Jerry L. Bauman, Jose Gallastegui, W. D. Bauma, Karen J. Beckman, Robert J. Hariman,
Tópico(s)Cardiac pacing and defibrillation studies
ResumoT he approved type IA antiarrhythmic drugs quinidine, procainamide and disopyramide are widely used in the treatment of cardiac rhythm disturbances and serum concentrations of these drugs are frequently obtained. These drug levels are routinely interpreted in the context of commonly cited “therapeutic ranges” and used to guide therapy decisions and manipulate dosages. The present study was undertaken to evaluate the value of isolated serum concentrations of antiarrhythmic drugs and to analyze the effect of concentration on concordance and discordance of response.
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