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Apoptosis as a proinflammatory event: What can we learn from bacteria-induced cell death?

1997; Elsevier BV; Volume: 5; Issue: 5 Linguagem: Inglês

10.1016/s0966-842x(97)01044-5

1878-4380

Arturo Zychlinsky, Philippe J. Sansonetti,

Viral gastroenteritis research and epidemiology

Infection of cells by some pathogenic bacteria triggers host cell apoptosis. Bacteria-induced apoptosis appears to promote an inflammatory response that causes tissue damage and further bacterial colonization. Shigella pathogenesis offers a paradigm for the role of apoptosis in bacterial infections.