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Women's opinion on withdrawal bleeding with hormone replacement therapy

1993; Elsevier BV; Volume: 51; Issue: 3 Linguagem: Inglês

10.1016/0028-2243(93)90036-c

1872-7654

R. Barentsen, Frans P.M.J. Groeneveld, Frits Bareman, Arno W. Hoes, H. J. Dokter, A. C. Drogendijk,

Menopause: Health Impacts and Treatments

The objective of the study was to assess the opinion of women about the use of hormone replacement therapy (HRT) in relation to continuation or re-induction of bleeding periods after menopause.The design was a population-based cross-sectional study using a postal questionnaire in Krimpen aan den IJssel, a commuter suburb of Rotterdam.The participants were all 2729 women living in Krimpen aan den IJssel aged 45-60 years, of whom 1947 (71.3%) responded.The main outcome measure was an opinion on monthly or trimonthly withdrawal bleedings with HRT.The results showed 16.9% of all women have no or little objection to use of HRT with monthly withdrawal bleedings.There is a marked difference between premenopausal women (32.4% have no or little objection) and postmenopausal women (only 9.2% have no or little objection).Trimonthly cycles during HRT tend to be perceived as more acceptable (41.4% of premenopausal women and 11.8% of postmenopausal women have no or little objection).It is concluded that a reasonable proportion of premenopausal women accept continuation of periodic bleeding with HRT.There is a preference for trimonthly cycles rather than monthly withdrawal bleedings.Most postmenopausal women object to having withdrawal bleedings with HRT, irrespective of a monthly or trimonthly cycle.Research should continue on schedules without withdrawal bleedings.