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Effective plaque removal with a new 8 French‐compatible atherectomy catheter

2002; Wiley; Volume: 56; Issue: 4 Linguagem: Inglês

10.1002/ccd.10196

1522-726X

Takuro Takagi, Carlo Di Mario, Goran Stanković, Bernhard Reimers, Alessandro Alberti, Francesco Liïstro, Oksana Kovalenko, Fabio Sgura, Remo Albiero, Flavio Ribichini, Alessandro Pugno, Antonio Colombo,

Cerebrovascular and Carotid Artery Diseases

Abstract The purpose of this study was to evaluate the safety and efficacy of the new 8 Fr guide catheter‐compatible Flexicut directional atherectomy device and to compare it with the conventional Atherocath GTO catheter. The 6 Fr Flexicut catheter has a larger cutting window and a titanium nitride‐coated cutter to effect more tissue removal as well as treat mildly calcified lesions. A group of 143 lesions in 117 consecutive patients treated with the Flexicut catheter in four centers were compared with a control group of 277 lesions in 212 consecutive patients treated with the GTO device. Postatherectomy luminal diameters were larger (2.92 ± 0.79 vs. 2.52 ± 0.64 mm; P < 0.0001), with more luminal gain (relative gain: 0.58 ± 0.24 vs. 0.48 ± 0.25; P = 0.0007) using fewer directional coronary atherectomy (DCA) cuts (12 ± 7 vs. 16 ± 9; P = 0.0001) in the Flexicut group. A residual diameter stenosis < 20% immediately after DCA was obtained in 77% of the lesions in the Flexicut group vs. 45% in the GTO group ( P < 0.0001). Histology in the former group revealed large calcium speckles in the retrieved specimens. In the Flexicut group, there was a lower incidence of access site complications and damage to the coronary ostium (2.5% vs. 7.5%; P = 0.08). The new Flexicut catheter is more effective than the conventional GTO catheter with a trend for reduced guiding catheter‐related complications. Cathet Cardiovasc Intervent 2002;56:452–459. © 2002 Wiley‐Liss, Inc.