Abnormal Brain Structure Implicated in Stimulant Drug Addiction
2012; American Association for the Advancement of Science; Volume: 335; Issue: 6068 Linguagem: Inglês
10.1126/science.1214463
ISSN1095-9203
AutoresKaren D. Ersche, P. Simon Jones, Guy Williams, Abigail J. Turton, Trevor W. Robbins, Edward T. Bullmore,
Tópico(s)Neurological disorders and treatments
ResumoAddiction to drugs is a major contemporary public health issue, characterized by maladaptive behavior to obtain and consume an increasing amount of drugs at the expense of the individual's health and social and personal life. We discovered abnormalities in fronto-striatal brain systems implicated in self-control in both stimulant-dependent individuals and their biological siblings who have no history of chronic drug abuse; these findings support the idea of an underlying neurocognitive endophenotype for stimulant drug addiction.
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