Artigo Acesso aberto Produção Nacional Revisado por pares

Antimicrobial activity of Hyptis ovalifolia towards dermatophytes

2003; Instituto Oswaldo Cruz, Ministério da Saúde; Volume: 98; Issue: 7 Linguagem: Inglês

10.1590/s0074-02762003000700018

ISSN

1678-8060

Autores

L. K. H. Souza, Cecília MA de Oliveira, Pedro Henrique Ferri, Juldásio Galdino de Oliveira Júnior, Ary Henrique de Souza Júnior, Orionalda de Fátima Lisboa Fernandes, Maria do Rosário R. Silva,

Tópico(s)

Nail Diseases and Treatments

Resumo

The essential oil and the aqueous, hexane and methanolic fractions from Hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of Microsporum canis, 10 of M. gypseum, 20 of Trichophyton rubrum and 20 of T. mentagrophytes. The extracts inhibited growth of the dermatophytes tested at different concentrations. The most biologically active was the essential oil from the leaves which inhibited 57 isolates (95%) at a concentration of £ 500 µg/ml.

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