Portal de Periódicos da CAPES

Risk factors and clinical course of portal and/or splenic vein thrombosis after partial splenic embolization

2009; SAGE Publishing; Volume: 50; Issue: 6 Linguagem: Inglês

10.1080/02841850902922779

1600-0455

Tomohiro Matsumoto, Takuji Yamagami, Koshi Terayama, Takeharu Kato, Tatsuya Hirota, Rika Yoshimatsu, Hiroshi Miura, Hirotoshi Ito, Takeshi Okanoue, Tsunehiko Nishimura,

Hepatocellular Carcinoma Treatment and Prognosis

Although portal and/or splenic vein thrombosis after partial splenic embolization (PSE) is a well-known complication, few reports evaluating risk factors have been published.To investigate risk factors and clinical course of portal and/or splenic vein thrombosis after PSE.Sixteen patients with severe hypersplenism underwent PSE between March 2005 and April 2008. The correlation between portal and/or splenic vein thrombosis after PSE detected on multidetector row CT (MDCT) and various factors were retrospectively reviewed. Further, the clinical course of portal and/or splenic vein thrombosis after PSE was observed on follow-up MDCT.Splenic vein thrombosis was detected in eight patients (50%) on MDCT images taken within 9 days after PSE. In one, the thrombosis also involved the portal vein. The infarct volume was identified as a significant risk factor for portal and/or splenic vein thrombosis (P=0.046). In all but one patient, splenic vein thrombosis resolved completely or improved without anticoagulation therapy. In this patient, both portal and splenic vein thrombosis developed after PSE, and anticoagulation therapy was necessary.It is suggested that a large splenic infarct volume is a risk factor for portal and/or splenic vein thrombosis after PSE. Indications for treatment of thrombosis of the portal vein system after PSE may be limited to patients with portal vein thrombosis.