Ketazolam and Diazepam in Anxiety: A Controlled Study
1980; Wiley; Volume: 20; Issue: 10 Linguagem: Inglês
10.1002/j.1552-4604.1980.tb01673.x
ISSN1552-4604
AutoresKarl Rickels, I Csanalosi, Paul Greisman, MERRILL J. MIRMAN, Richard J. Morris, Charles C. Weise, G Weiß,
Tópico(s)Treatment of Major Depression
ResumoKetazolam (both in once-daily and three-times-daily dosing), diazepam, and placebo were compared for effectiveness in relieving anxious symptomatology in a clinical trial conducted with a total of 222 anxious, non-psychotic outpatients. Results indicated that improvement occurred early in treatment, that ketazolam was equally effective in both once-daily and three-times-daily dosing, and that ketazolam was similar in effect to diazepam. Ketazolam (both once-daily and three-times-daily) and diazepam were significantly (P < 0.05) better than placebo in alleviating symptoms of anxiety, as measured by the Hamilton Anxiety Scale, the Covi Anxiety Scale, and a physician-rated measure of global improvement.
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