Portal de Periódicos da CAPES

The Area under the Plasma Concentration Curve (AUC) of Urethane in Mice and the Influence of Concomitant Administration of Ethanol

1994; Wiley; Volume: 75; Issue: 5 Linguagem: Inglês

10.1111/j.1600-0773.1994.tb00369.x

1600-0773

Eva Kristiansen, Martin Vahl, Ole Ladefoged, Otto Meyer, Grete Østergaard, Henrik Rye Lam,

Regulation of Appetite and Obesity

Pharmacology & ToxicologyVolume 75, Issue 5 p. 324-326 The Area under the Plasma Concentration Curve (AUC) of Urethane in Mice and the Influence of Concomitant Administration of Ethanol Eva Kristiansen, Corresponding Author Eva Kristiansen Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkAuthor for correspondence: Eva Kristiansen, Institute of Toxicology, National Food Agency, 19, Mørkhøj Bygade, DK-2860 Søborg, Denmark (fax +45 39 66 01 00).Search for more papers by this authorMartin Vahl, Martin Vahl Institute of Food Chemistry and Nutrition, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this authorOle Ladefoged, Ole Ladefoged Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this authorOtto Meyer, Otto Meyer Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this authorGrete Østergaard, Grete Østergaard Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this authorHenrik Rye Lam, Henrik Rye Lam Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this author Eva Kristiansen, Corresponding Author Eva Kristiansen Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkAuthor for correspondence: Eva Kristiansen, Institute of Toxicology, National Food Agency, 19, Mørkhøj Bygade, DK-2860 Søborg, Denmark (fax +45 39 66 01 00).Search for more papers by this authorMartin Vahl, Martin Vahl Institute of Food Chemistry and Nutrition, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this authorOle Ladefoged, Ole Ladefoged Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this authorOtto Meyer, Otto Meyer Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this authorGrete Østergaard, Grete Østergaard Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this authorHenrik Rye Lam, Henrik Rye Lam Institute of Toxicology, National Food Agency, 19, Morkhøj Bygade, DK-2860 Søborg, DenmarkSearch for more papers by this author First published: November 1994 https://doi.org/10.1111/j.1600-0773.1994.tb00369.xCitations: 3AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References Altmann, H.-J., B. Dusemund, M. Goll & W. Grunow: Effect of ethanol on the induction of lung tumours by ethyl carbamate in mice. Toxicology 1991, 68, 195– 201. Kristiansen, E., S. Clemmensen & O. Meyer: Chronic ethanol intake and reduction of lung tumours from urethane in strain A mice. Fd. Chem. Toxic. 1990, 28, 35– 38. Kurata, N., H. E. Hurst, F. W. Benz, R. A. Kemper & W. J. Waddell: Studies on inhibition and induction of metabolism of ethyl carbamate by acetone and related compounds. Drug Metab. Dispos. 1991, 19, 388– 393. Nomeir, A. A., Y. M. Ioannou, J. M. Sanders & H. B. Matthews: Comparative metabolism and disposition of ethyl carbamate (urethane) in male Fischer 344 rats and male B6C3Fl mice. Toxicol. Appl. Pharmacol. 1989, 91, 203– 215. O'Flaherty, E. J. & S. P. Sichak: The kinetics of urethane elimination in the mouse. Toxicol. Appl. Pharmacol. 1983, 68, 354– 358. Schlatter, J. & W. K. Lutz: The carcinogenic potential of ethyl carbamate (urethane): risk assessment at human dietary exposure levels. Fd. Chem. Toxic. 1990, 28, 205– 211. Uggla, A. & L. Busk: Ethyl carbamate (urethane) in alcoholic beverages and foodstuffs - A Nordic View. Nordiske Seminar og Arbejdsrapporter 1992: 570. Nordic Council of Ministers, Copenhagen. Vahl, M.: A survey of ethyl carbamate in beverages, bread and acidified milks sold in Denmark. Fd. Add. Contam. 1993, 10, 585– 592. Waddell, W. J., C. Marlowe & W. M. Pierce: Inhibition of the localization of urethane in mouse tissues by ethanol. Fd. Chem. Toxic. 1987, 25, 527– 531. Yamamoto, X., W. M. Pierce, H. E. Hurst, D. Chen & W. J. Waddell: Inhibition of the metabolism of urethane by ethanol. Drug Metab. Dispos. 1988, 16, 355– 358. Zimmerli, B. & J. Schlatter: Ethyl carbamate: analytical methodology, occurrence, formation, biological activity and risk assessment. Mutat. Res. 1991, 259, 325– 350. Citing Literature Volume75, Issue5November 1994Pages 324-326 ReferencesRelatedInformation