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COMPUTER ANALYSIS OF DRUG‐PROTEIN BINDING DATA*

1973; Wiley; Volume: 226; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1973.tb20469.x

1749-6632

John Fletcher, J. Douglas Ashbrook, Arthur A. Spector,

Metabolomics and Mass Spectrometry Studies

Annals of the New York Academy of SciencesVolume 226, Issue 1 p. 69-81 COMPUTER ANALYSIS OF DRUG-PROTEIN BINDING DATA* John E. Fletcher, John E. Fletcher Laboratory of Applied Studies Division of Computer Research and Technology National Institutes of Health Bethesda, Maryland 20014Search for more papers by this authorJ. Douglas Ashbrook, J. Douglas Ashbrook Laboratory of Applied Studies Division of Computer Research and Technology National Institutes of Health Bethesda, Maryland 20014Search for more papers by this authorArthur A. Spector, Arthur A. Spector Departments of Biochemistry and Internal Medicine University of Iowa Iowa City, Iowa 52240Search for more papers by this author John E. Fletcher, John E. Fletcher Laboratory of Applied Studies Division of Computer Research and Technology National Institutes of Health Bethesda, Maryland 20014Search for more papers by this authorJ. Douglas Ashbrook, J. Douglas Ashbrook Laboratory of Applied Studies Division of Computer Research and Technology National Institutes of Health Bethesda, Maryland 20014Search for more papers by this authorArthur A. Spector, Arthur A. Spector Departments of Biochemistry and Internal Medicine University of Iowa Iowa City, Iowa 52240Search for more papers by this author First published: November 1973 https://doi.org/10.1111/j.1749-6632.1973.tb20469.xCitations: 46 * A portion of this work was supported by research grants from the National Institutes of Health (HL-14, 781) and the American Heart Association (71-895) in addition to a Research Career Development Award from the National Institutes of Health (K4-HL-20, 338). AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Scatchard, G., W. L. Hughes, Jr., F. R. N. Gurd & P. E. Wilcox 1954. The interaction of proteins with small molecules and ions. In Chemical Specificity in Biological Interactions. F. R. N. Gurd, Ed.: 193–219. Academic Press. New York , N.Y . 2 Scatchard, G. 1949. The attractions of proteins for small molecules and ions. Ann. N. Y. Acad. Sci. 51: 660–672. 3 Steinhardt, J. & J. A. Reynolds 1969. Multiple Equilibria in Proteins.: 1–9. Academic Press. New York , N.Y . 4 Fletcher, J. E., A. A. Spector & J. D. Ashbrook 1970. Analysis of macromolecule-ligand binding by determination of stepwise equilibrium constants. Biochemistry 9: 4580–4587. 5 Fletcher, J. E. & A. A. Spector 1968. A procedure for computer analysis of data from macromolecule-ligand binding studies. Comput. Biomed. Res. 2: 164–175. 6 Fletcher, J. E. & R. I. Shrager 1968. A User's Guide to Least Squares Model Fitting. DCRT Tech. Rep. No. 1. National Institutes of Health. Bethesda , MD . 7 Shrager, R. I. 1970. MODELAIDE: A Computer Graphics Program for the Evaluation of Mathematical Models. DCRT Tech. Rep. No. 5. National Institutes of Health. Bethesda , MD . Citing Literature Volume226, Issue1Drug‐Protein BindingNovember 1973Pages 69-81 ReferencesRelatedInformation