Epidemiology of nausea and vomiting of pregnancy: prevalence, severity, determinants, and the importance of race/ethnicity
2009; BioMed Central; Volume: 9; Issue: 1 Linguagem: Inglês
10.1186/1471-2393-9-26
ISSN1471-2393
AutoresAnaïs Lacasse, Évelyne Rey, Ema Ferreira, Caroline Morin, Anick Bérard,
Tópico(s)Folate and B Vitamins Research
ResumoAbstract Background Studies that contributed to the epidemiology of nausea and vomiting of pregnancy have reported conflicting findings, and often failed to account for all possible co-variables necessary to evaluate the multidimensional associations. The objectives of this study were to: 1) Estimate the prevalence and the severity of nausea and vomiting of pregnancy during the 1 st and the 2 nd trimester of pregnancy, and 2) Identify determinants of presence and severity of nausea and vomiting of pregnancy during the 1 st and 2 nd trimesters separately, with a special emphasis on the impact of race/ethnicity. Methods A prospective study including pregnant women attending the Centre Hospitalier Universitaire (CHU) Sainte-Justine or René-Laennec clinics for their prenatal care was conducted from 2004 to 2006. Women were eligible if they were ≥ 18 years of age, and ≤ 16 weeks of gestation. Women were asked to fill out a 1 st trimester self-administered questionnaire and were interviewed over the telephone during their 2 nd trimester of pregnancy. Presence of nausea and vomiting of pregnancy was based on the reporting of pregnant women (yes/no); severity of symptoms was measured by the validated modified-PUQE index. Results Of the 367 women included in the study, 81.2% were Caucasians, 10.1% Blacks, 4.6% Hispanics, and 4.1% Asians. Multivariate analyses showed that race/ethnicity was significantly associated with a decreased likelihood of reporting nausea and vomiting of pregnancy (Asians vs. Caucasians OR: 0.13; 95%CI 0.02–0.73; and Blacks vs. Caucasians OR: 0.29; 95%CI 0.09–0.99). Conclusion Our study showed that race/ethnicity was associated with the reporting of nausea and vomiting of pregnancy in the 1 st trimester of pregnancy.
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