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Chronic hemolytic anemia with paroxysmal nocturnal hemoglobinuria (marchiafava-micheli syndrome)

1943; Elsevier BV; Volume: 22; Issue: 1 Linguagem: Inglês

10.1016/s0022-3476(43)80138-4

1097-6833

Paul P. Pierce, C. Anderson Aldrich,

Complement system in diseases

Another case of chronic hemolytic anemia with paroxysmal nocturnal hemoglobinuria is reported. The patient, a child 5 years of age, is the youngest to appear in the literature. Thrombocytopenia was marked in this case, and purpuric manifestations were present. Splenectomy was performed. The essential features of the disease except the thrombocytopenia were not altered by this treatment.