The effect of liver enzyme inhibition by cimetidine and enzyme induction by phenobarbitone on the pharmacokinetics of paroxetine
1989; Wiley; Volume: 80; Issue: S350 Linguagem: Inglês
10.1111/j.1600-0447.1989.tb07184.x
ISSN1600-0447
AutoresW. H. Greb, G. Büscher, H.‐D. Dierdorf, F. E. Köster, David S. Wolf, G. Mellows,
Tópico(s)Antibiotics Pharmacokinetics and Efficacy
ResumoActa Psychiatrica ScandinavicaVolume 80, Issue S350 p. 95-98 The effect of liver enzyme inhibition by cimetidine and enzyme induction by phenobarbitone on the pharmacokinetics of paroxetine W. H. Greb, W. H. Greb Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorG. Buscher, G. Buscher Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorH.-D. Dierdorf, H.-D. Dierdorf Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorF. E. Köster, F. E. Köster Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorD. Wolf, D. Wolf Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorG. Mellows, G. Mellows *Beecham Pharmaceuticals Research Division, Medicinal Research Centre, Harlow, Essex, United KingdomSearch for more papers by this author W. H. Greb, W. H. Greb Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorG. Buscher, G. Buscher Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorH.-D. Dierdorf, H.-D. Dierdorf Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorF. E. Köster, F. E. Köster Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorD. Wolf, D. Wolf Beecham-Wülfing Clinical Pharmacology Research Institute, Neuss, Federal Republic of GermanySearch for more papers by this authorG. Mellows, G. Mellows *Beecham Pharmaceuticals Research Division, Medicinal Research Centre, Harlow, Essex, United KingdomSearch for more papers by this author First published: June 1989 https://doi.org/10.1111/j.1600-0447.1989.tb07184.xCitations: 26AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Dossing M., Pilsgaard H., Rasmussen B., et al. Time course of phenobarbital and cimetidine mediated changes in hepatic drug metabolism. Eur J Clin Pharmacol 1983: 25: 215–222. 10.1007/BF00543794 PubMedWeb of Science®Google Scholar 2 Rowland M., Tozer TN. Clinical Pharmacokinetics. Philadelphia : Lea & Febiger, 1980: 147 150. Google Scholar 3 Shaheen O., Branch RA. Pharmacokinetic drug interaction with cimetidine. Ration Drug Ther 1986: 20: 1–6. PubMedGoogle Scholar 4 Brett MA., Dierdorf H.-D., Zussman BD., Coates PE. Determination of paroxetine in human plasma, using high-performance liquid chromatography with fluorescence detection. J Chromatogr 1987: 419: 438–444. 10.1016/0378-4347(87)80313-4 CASPubMedWeb of Science®Google Scholar 5 Bodemar G., Walan A. Maintenance treatment of recurrent peptic ulcer by cimetidine. Lancet 1978: 2: 403–407. 10.1016/S0140-6736(78)91200-X PubMedWeb of Science®Google Scholar 6 Burgess E., Cutler RE., Blair AD. Cimetidine pharmaco-kinetics in hemodialysis patients and inhibition of creatinine secretion in healthy subjects. Clin Pharmacol Ther 1980: 27: 247. Web of Science®Google Scholar 7 Haddock RE., Jackson D., Wood FR. Paroxetine: lack of effect on hepatic drug metabolizing enzymes. Acta Psychiatr Scand 1989: 80 (Suppl. 350): 93–94. 10.1111/j.1600-0447.1989.tb07183.x Web of Science®Google Scholar Citing Literature Volume80, IssueS350June 1989Pages 95-98 ReferencesRelatedInformation
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