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1570 CUTANEOUS CORPUSCULAR RECEPTORS OF THE HUMAN GLANS CLITORIS: DESCRIPTIVE CHARACTERISTICS AND COMPARISON WITH THE GLANS PENIS

2013; Lippincott Williams & Wilkins; Volume: 189; Issue: 4S Linguagem: Inglês

10.1016/j.juro.2013.02.3120

1527-3792

Cheryl Shih, Christopher J. Cold, Claire C. Yang,

Genital Health and Disease

You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Female Urology (I)1 Apr 20131570 CUTANEOUS CORPUSCULAR RECEPTORS OF THE HUMAN GLANS CLITORIS: DESCRIPTIVE CHARACTERISTICS AND COMPARISON WITH THE GLANS PENIS Cheryl Shih, Christopher Cold, and Claire Yang Cheryl ShihCheryl Shih Seattle, WA More articles by this author , Christopher ColdChristopher Cold Marshfield, WI More articles by this author , and Claire YangClaire Yang Seattle, WA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.3120AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The female genital sensory pathways that initiate sexual arousal reflexes begin with cutaneous corpuscular receptors in the glabrous genital skin, including those of the glans clitoris. The purpose of this study was to characterize the corpuscular receptors of the glans clitoris. In addition, we compared basic features with the receptors of the glans penis. METHODS Five cadaveric vulvectomy specimens and four cadaveric penile specimens were used. They were serially sectioned and stained with hematoxylin and eosin. Selected blocks were stained with Masson's trichrome, and immunohistochemical staining was done with neuronal markers S-100 and neurofilament. RESULTS Using the three stains, we identified an abundance of corpuscular receptors within the glans clitoris, as compared to the surrounding prepuce. These receptors were of varied arrangements, situated in the subepithelial tissues of the glans clitoris. They were indistinguishable from the receptors of the glans penis. The number of receptors per 100x high-powered field ranged from 1 to 14; whereas, the receptor density in the glans penis ranged from 1 to 3 (Table). Figure 1: Section along the long-axis of the glans clitoris, low power. Note the high density of corpuscular receptors (stained dark brown) within the glans (*) as compared to the preputial skin of the clitoral hood (CH). S100 stain, 20x. Figure 2: Large corpuscular sensory receptor abutting the epithelium of the glans clitoris. Neurofilament stain, 400x. CONCLUSIONS The glans clitoris is densely innervated with cutaneous corpuscular receptors, and these receptors are morphologically similar to the corpuscular receptors of the glans penis. The glans clitoris has greater variability in receptor density compared to the glans penis. Corpuscular receptors per 100x high powered field (HPF) Specimen Glans Penis1 Glans Clitoris2 1 2 14 2 3 7 3 1 6 4 2 1 Average 2.0 7.0 1 The glans penis was divided into 4 regions (dorsum, ventrum/frenulum, right lateral, left lateral). The average number of corpuscular receptors per HPF, or density, of each region was recorded. The dorsum density for each specimen was used for comparison to the glans clitoris. 2 The dorsum of the glans clitoris was considered as a single specimen, and the average number of corpuscular receptors per HPF for each specimen was recorded. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e644-e645 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Cheryl Shih Seattle, WA More articles by this author Christopher Cold Marshfield, WI More articles by this author Claire Yang Seattle, WA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...