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Association between Hypothyroidism and Small Intestinal Bacterial Overgrowth

2007; Oxford University Press; Volume: 92; Issue: 11 Linguagem: Inglês

10.1210/jc.2007-0606

1945-7197

E.C. Lauritano, Anna Lisa Bilotta, Maurizio Gabrielli, Emidio Scarpellini, A. Lupascu, Antonio Laginestra, M. Novi, S. Sottili, Michele Serricchio, Giovanni Cammarota, Antonio Gasbarrini, Alfredo Pontecorvi, Antonio Gasbarrini,

Gastrointestinal motility and disorders

Objectives: Small intestinal bacterial overgrowth is defined as an abnormally high bacterial population level in the small intestine. Intestinal motor dysfunction associated with hypothyroidism could predispose to bacterial overgrowth. Luminal bacteria could modulate gastrointestinal symptoms and interfere with levothyroxine absorption. The aims of the present study were to assess the prevalence and clinical pattern of bacterial overgrowth in patients with a history of overt hypothyroidism and the effects of bacterial overgrowth decontamination on thyroid hormone levels.