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AURAL MANIFESTATIONS OF LEUKEMIA

1945; American Medical Association; Volume: 42; Issue: 4 Linguagem: Inglês

10.1001/archotol.1945.00680040351005

1538-361X

J. G. DRUSS,

Vestibular and auditory disorders

In 1856, nine years after Virchow had established leukemia as a definite clinical entity, Vidal made the significant observation that disturbances of hearing were often associated with this disease. While this observation was subsequently confirmed by other investigators, it remained for Politzer 1 in 1884 to lay the groundwork for the present knowledge of the pathologic changes that occur in the ear in leukemia. He was the first to section the temporal bones in a case of myelogenous leukemia and to correlate the clinical with the pathologic observations. There soon followed reports of individual cases with necropsies by Gradenigo, 2 Steinbrugge, 3 Waggenhauser 4 and others. In 1897 Schwabach 5 reviewed 15 cases, 10 previously reported by others, to which were added 5 of his own. Reports of single cases by the English authors Weber and Lake, 6 Finlaysin 7 and Mott 8 then appeared in the literature. In 1906 Alexander 9 published a comprehensive monograph on the subject