Produção Nacional
Revisado por pares
Multirresistência a antimicrobianos mediada por plasmídios R em cepas de Shigella flexneri isoladas no nordeste do Brasil
1998; Brazilian Society of Tropical Medicine; Volume: 31; Issue: 3 Linguagem: Inglês
10.1590/s0037-86821998000300003
ISSN1678-9849
AutoresJosé Júlio Costa Sidrim, José Luciano Bezerra Moreira, Germana Costa Paixão, Sergio Bezerra Lima, Renato Evandro M. Filho, Marcos Fábio Gadelha Rocha, Aldo Â. M. Lima,
Tópico(s)Escherichia coli research studies
ResumoIn Shigella strains were studied the molecular mechanism that mediated the multiply antibiotic-resistance. Twenty-six strains of Shigella flexneri were utilised in this investigation. These strains were submitted to disk diffusion test, mating experiments and plasmid isolation. In relation to antibiotics resistance standard it was observed that all Shigella flexneri strains were resistant to at least, three antibiotics tested. From twenty-six Shigella flexneri strains donors submitted to conjugation process, 34.6% (nine strains) resulted in variable frequency of transconjugants. From strains that conjugated, 100%, transferred the resistance factor acquainted with ampicillin. Being that, in all transconjugants which were observed, just one plasmid with 23.1 Kb was evidenced. This plasmid found in all strains was characterised as the cause of resistance to ampicillin.
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