EFFECT OF SUNLIGHT ON THE CLINICAL MANIFESTATIONS OF PELLAGRA
1937; American Medical Association; Volume: 59; Issue: 4 Linguagem: Inglês
10.1001/archinte.1937.00170200073006
ISSN1538-3679
Autores Tópico(s)Drug-Induced Ocular Toxicity
ResumoThe influence of the sun's rays on the lesions of pellagra has been a subject of debate for nearly two hundred years. Casal 1 noted a seasonal variation in the incidence of pellagra, with a peak which corresponded to the spring equinox. In Italy one of the common names applied to this disease by the peasants is mal del sole (disease of the sun), while certain Italian physicians have described the lesions as due to "sunstroke of the skin." 2 Many modern clinicians 3 have stated their conviction that there is a close relationship between exposure to sunlight and the development of cutaneous lesions in a pellagrin. Various observers 4 have produced typical cutaneous lesions in pellagrins by exposing normal or recently healed areas of skin to direct sunlight. Gherardini 3w demonstrated the effect of the sun by systematically uncovering various parts of the body of each patient. Bouchard, 3b Hameau 3x and Ormsby 4a
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