Increases of neuropeptide Y-like immunoreactivity in plasma during insulin-induced hypoglycemia in man
1988; Elsevier BV; Volume: 9; Issue: 2 Linguagem: Inglês
10.1016/0196-9781(88)90281-1
ISSN1873-5169
AutoresKazuhiro Takahashi, Toraichi Mouri, Osamu Murakami, Keiichi Itoi, Masahiko Sone, Makoto Ohneda, Mitsuru Nozuki, KAORU YOSHINAGA,
Tópico(s)Regulation of Appetite and Obesity
ResumoNeuropeptide Y-like immunoreactivity (NPY-LI) in plasma during insulin-induced hypoglycemia was measured in 4 healthy male volunteers. Plasma NPY-LI increased from 167±11 pg/ml to 247±25 pg/ml 30 min after the administration of insulin (0.1 U/kg body weight IV), reached the maximum (296±6 pg/ml) 45 min after the insulin, and then decreased. These results suggest that NPY is released into the systemic circulation during insulin-induced hypoglycemia in man.
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