A stereodivergent asymmetric approach to difluorinated aldonic acids
2004; Royal Society of Chemistry; Issue: 13 Linguagem: Inglês
10.1039/b405067c
ISSN1364-548X
AutoresChristophe Audouard, Igor Barsukov, John Fawcett, Gerry A. Griffith, Jonathan M. Percy, Stéphane Pintat, Clive A. Smith,
Tópico(s)Asymmetric Synthesis and Catalysis
ResumoA (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.
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