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Substituted Pyrazolopyridines as Potent and Selective PDE5 Inhibitors: Potential Agents for Treatment of Erectile Dysfunction

2001; American Chemical Society; Volume: 44; Issue: 7 Linguagem: Inglês

10.1021/jm0155042

1520-4804

Guixue Yu, Helen J. Mason, Ximao Wu, Jian Wang, Saeho Chong, Gary Dorough, Andrew Henwood, Ronald Pongrac, Laurie Seliger, Bin He, Diane E. Normandin, Leonard P. Adam, John Krupinski, John E. Macor,

Neuropeptides and Animal Physiology

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTSubstituted Pyrazolopyridines as Potent and Selective PDE5 Inhibitors: Potential Agents for Treatment of Erectile DysfunctionGuixue Yu, Helen J. Mason, Ximao Wu, Jian Wang, Saeho Chong, Gary Dorough, Andrew Henwood, Ronald Pongrac, Laurie Seliger, Bin He, Diane Normandin, Leonard Adam, John Krupinski, and John E. MacorView Author Information Discovery Chemistry, Drug Metabolism and Pharmacokinetics, Drug Safety, and Metabolic & Cardiovascular Drug Discovery, Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 5400, Princeton, New Jersey 08543-5400 Cite this: J. Med. Chem. 2001, 44, 7, 1025–1027Publication Date (Web):March 6, 2001Publication History Received18 January 2001Published online6 March 2001Published inissue 1 March 2001https://doi.org/10.1021/jm0155042Copyright © 2001 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views795Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (47 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Amides,Inhibition,Inhibitors,Rodent models,Selectivity Get e-Alerts