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BIBTEX RIS

The E-selectin gene polymorphism and carotid atherosclerosis in end-stage renal disease

2006; Oxford University Press; Volume: 21; Issue: 7 Linguagem: Inglês

10.1093/ndt/gfl115

ISSN

1460-2385

Autores

A. Testa, Francesco Benedetto, Belinda Spoto, Anna Pisano, Giovanni Tripepi, Francesca Mallamaci, Lorenzo Malatino, Carmine Zoccali,

Tópico(s)

Adipokines, Inflammation, and Metabolic Diseases

Resumo

Background. E-selectin is a cell surface glycoprotein that mediates the adhesion of leucocytes to vessels endothelium, an important early step in the atherosclerotic process. End-stage renal disease (ESRD) is a highly atherogenic disease but it is unknown whether genetic polymorphism(s) in the E-selectin gene plays a role in the severity of arterial damage in this condition.

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