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Cytogenetic analysis of a congenital fibrosarcoma

1991; Elsevier BV; Volume: 52; Issue: 1 Linguagem: Inglês

10.1016/0165-4608(91)90051-u

1873-4456

L. Adam, E. V. Davison, Archie J. Malcolm, Andrew D.J. Pearson, Alan Craft,

Tumors and Oncological Cases

Congenital (infantile) fibrosarcoma is a rare soft tissue sarcoma occurring in children aged less than 5 years. We performed cytogenetic analysis on such a tumor, which had an abnormal karyotype: 48,XY, +11, +20. Three other reports of karyotypes in congenital fibrosarcoma describe similar cytogenetic changes, and a specific pattern of trisomies that may prove diagnostic for this tumor is beginning to emerge.