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Aerosol fabrication of hollow mesoporous silica nanoparticles and encapsulation of l-methionine as a candidate drug cargo

2010; Royal Society of Chemistry; Volume: 46; Issue: 17 Linguagem: Inglês

10.1039/b927025f

1364-548X

Xingmao Jiang, Timothy L. Ward, Yung‐Sung Cheng, Juewen Liu, C. Jeffrey Brinker,

Dendrimers and Hyperbranched Polymers

Hollow spherical nanoparticles with ordered mesoporous silica shells were fabricated by evaporation-induced self-assembly using (NH4)2SO4 and cetyltrimethyl ammonium bromide (CTAB) as templates. The model drug, L-methionine, was encapsulated within the spherical void at high loadings by repeated crystallization.