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Binding of a specific subclass of immunoglobulins by a human seminal plasma component

2009; Wiley; Volume: 25; Issue: 5 Linguagem: Inglês

10.1111/j.1439-0272.1993.tb02725.x

1439-0272

Zhi Liang, Masamitsu Kamada, S. S. Koide,

Blood groups and transfusion

Summary. Human seminal plasma contains a component that binds immunoglobulins (Ig). The Ig binding factor was purified by ammonium sulphate precipitation, preparative isoelectro-focusing and gel filtration chromatography and found to bind strongly human IgGl and mouse IgM. This seminal plasma component may possess immunosuppressive activity and may modulate the activities of the immunosurveillance system of the reproductive tract.