Effect of Influenza Vaccination of Children on Infection Rates in Hutterite Communities
2010; American Medical Association; Volume: 303; Issue: 10 Linguagem: Inglês
10.1001/jama.2010.250
ISSN1538-3598
AutoresMark Loeb, Margaret L. Russell, Lorraine Moss, Kevin Fonseca, Julie D. Fox, David J. D. Earn, Fred Y. Aoki, Gregory Horsman, Paul Van Caeseele, Khami Chokani, Mark Vooght, Lorne A. Babiuk, Richard J. Webby, Stephen D. Walter,
Tópico(s)Respiratory viral infections research
Resumo2][3][4] During pandemics, the burden of influenza illness increases substantially. 5Current vaccine policy focuses on immunizing those at high risk of complications of influenza. 6As a component of a broader policy to prevent the spread of influenza and reduce its complications, using immunization to interrupt communitywide transmission of influenza may be effective for protecting the entire population, including those at high risk. 7hildren and adolescents appear to play an important role in the transmission of influenza. 8-102][13][14][15][16][17][18] Nonrandomized designs, unblinded studies, or lack of laboratory confirmation of influenza limit the ability to draw conclusions, [12][13][14][15][16][17][18] particularly the potential for inactivated in-fluenza vaccine to achieve a herd effect.A systematic review concluded that although evidence exists that vaccinat-
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